I57V (p.Ile57Val) variant of PRKCA (Protein kinase C alpha type)
I57V (p.Ile57Val) in PRKCA (Protein kinase C alpha type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
I57V (p.Ile57Val) variant details
- p.Ile57Val
- TOPMed rs1231145168
- gnomAD rs1231145168
- Missense
- Variant Prioritization Score for Impact Estimate 0.596
- REVEL 0.60
- CADD 26.20
- PolyPhen-2 0.46
- SIFT 0.01
- Population evidence available
- Structural context available