H32L (p.His32Leu) variant of PRKCA (Protein kinase C alpha type)
H32L (p.His32Leu) in PRKCA (Protein kinase C alpha type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
H32L (p.His32Leu) variant details
- p.His32Leu
- gnomAD 17-66302946-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.58
- REVEL 0.46
- CADD 22.80
- PolyPhen-2 0.02
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available