D94N (p.Asp94Asn) variant of PRKCA (Protein kinase C alpha type)
D94N (p.Asp94Asn) in PRKCA (Protein kinase C alpha type) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
D94N (p.Asp94Asn) variant details
- p.Asp94Asn
- rs758445868
- NCI-TCGA Cosmic COSV5258
- ExAC rs758445868
- TOPMed rs758445868
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.19
- CADD 23.40
- PolyPhen-2 0.05
- SIFT 0.19
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available