D90E (p.Asp90Glu) variant of PRKCA (Protein kinase C alpha type)
D90E (p.Asp90Glu) in PRKCA (Protein kinase C alpha type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
D90E (p.Asp90Glu) variant details
- p.Asp90Glu
- gnomAD 17-66496265-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.25
- CADD 16.90
- PolyPhen-2 0.03
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available