C86W (p.Cys86Trp) variant of PRKCA (Protein kinase C alpha type)
C86W (p.Cys86Trp) in PRKCA (Protein kinase C alpha type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
C86W (p.Cys86Trp) variant details
- p.Cys86Trp
- gnomAD 17-66496253-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.606
- REVEL 0.88
- CADD 21.90
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available