A89V (p.Ala89Val) variant of PRKCA (Protein kinase C alpha type)
A89V (p.Ala89Val) in PRKCA (Protein kinase C alpha type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
A89V (p.Ala89Val) variant details
- p.Ala89Val
- TOPMed rs915754719
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.24
- CADD 22.60
- PolyPhen-2 0.04
- SIFT 0.25
- Population evidence available
- Structural context available