Y21H (p.Tyr21His) variant of PRKAR1A (P10644)
Y21H (p.Tyr21His) in PRKAR1A (P10644) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
Y21H (p.Tyr21His) variant details
- p.Tyr21His
- ExAC rs769019433
- gnomAD rs769019433
- Missense
- Variant Prioritization Score for Impact Estimate 0.669
- CADD 29.30
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available