R16R (p.Arg16Arg) variant of PRKAR1A (P10644)
R16R (p.Arg16Arg) in PRKAR1A (P10644) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
R16R (p.Arg16Arg) variant details
- p.Arg16Arg
- rs886041228
- gnomAD 17-68515445-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.618
- AlphaMissense 0.26
- MetaLR 0.46
- MetaSVM -0.07
- CADD 18.70
- PolyPhen-2 0.35
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available