H25R (p.His25Arg) variant of PRKAR1A (P10644)
H25R (p.His25Arg) in PRKAR1A (P10644) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
H25R (p.His25Arg) variant details
- p.His25Arg
- gnomAD 17-68515473-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.589
- CADD 22.70
- PolyPhen-2 0.07
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available