E19A (p.Glu19Ala) variant of PRKAR1A (P10644)
E19A (p.Glu19Ala) in PRKAR1A (P10644) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
E19A (p.Glu19Ala) variant details
- p.Glu19Ala
- ExAC rs780569077
- gnomAD rs780569077
- Missense
- Variant Prioritization Score for Impact Estimate 0.644
- CADD 27.60
- PolyPhen-2 0.55
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available