T26S (p.Thr26Ser) variant of PRKAA2 (P54646)
T26S (p.Thr26Ser) in PRKAA2 (P54646) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
T26S (p.Thr26Ser) variant details
- p.Thr26Ser
- gnomAD 1-56645464-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.266
- REVEL 0.10
- MetaLR 0.02
- MetaSVM -1.02
- CADD 18.70
- PolyPhen-2 0.13
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 9.5e-07)
- Structural context available
- Literature evidence available