G25R (p.Gly25Arg) variant of PRKAA2 (P54646)
G25R (p.Gly25Arg) in PRKAA2 (P54646) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data, published literature, and structural context.
G25R (p.Gly25Arg) variant details
- p.Gly25Arg
- gnomAD 1-56645460-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.873
- REVEL 0.95
- MetaLR 0.87
- MetaSVM 1.05
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.5e-07)
- Structural context available
- Literature evidence available