S65T (p.Ser65Thr) variant of PRKAA1 (Q13131)
S65T (p.Ser65Thr) in PRKAA1 (Q13131) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
S65T (p.Ser65Thr) variant details
- p.Ser65Thr
- TOPMed rs1412797330
- gnomAD rs1412797330
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- REVEL 0.14
- MetaLR 0.26
- MetaSVM -0.64
- CADD 23.70
- PolyPhen-2 0.21
- SIFT 0.09
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available