S5G (p.Ser5Gly) variant of PRKAA1 (Q13131)
S5G (p.Ser5Gly) in PRKAA1 (Q13131) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S5G (p.Ser5Gly) variant details
- p.Ser5Gly
- NCI-TCGA TCGA novel
- TOPMed rs1745029710
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.08
- CADD 23.00
- PolyPhen-2 0.00
- SIFT 0.28
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available