R21W (p.Arg21Trp) variant of PRKAA1 (Q13131)
R21W (p.Arg21Trp) in PRKAA1 (Q13131) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
R21W (p.Arg21Trp) variant details
- p.Arg21Trp
- Ensembl rs2112122231
- Missense
- Variant Prioritization Score for Impact Estimate 0.464
- REVEL 0.40
- MetaLR 0.27
- MetaSVM -0.60
- CADD 28.40
- PolyPhen-2 0.00
- SIFT 0.05
- Population evidence available
- Structural context available