K15R (p.Lys15Arg) variant of PRKAA1 (Q13131)
K15R (p.Lys15Arg) in PRKAA1 (Q13131) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
K15R (p.Lys15Arg) variant details
- p.Lys15Arg
- TOPMed rs1469720215
- gnomAD rs1469720215
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.10
- MetaLR 0.16
- MetaSVM -0.93
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available