G25R (p.Gly25Arg) variant of PRKAA1 (Q13131)
G25R (p.Gly25Arg) in PRKAA1 (Q13131) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
G25R (p.Gly25Arg) variant details
- p.Gly25Arg
- ExAC rs759922711
- TOPMed rs759922711
- gnomAD rs759922711
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.30
- MetaLR 0.09
- MetaSVM -1.09
- CADD 27.30
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available