S22G (p.Ser22Gly) variant of PPP2R5D (Q14738)
S22G (p.Ser22Gly) in PPP2R5D (Q14738) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S22G (p.Ser22Gly) variant details
- p.Ser22Gly
- TOPMed rs1190348868
- gnomAD rs1190348868
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.06
- MetaLR 0.04
- MetaSVM -1.12
- CADD 19.00
- PolyPhen-2 0.00
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available