P21S (p.Pro21Ser) variant of PPP2R5D (Q14738)
P21S (p.Pro21Ser) in PPP2R5D (Q14738) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
P21S (p.Pro21Ser) variant details
- p.Pro21Ser
- ExAC rs773110780
- gnomAD rs773110780
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.09
- MetaLR 0.06
- MetaSVM -0.94
- CADD 18.40
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available