G76G (p.Gly76Gly) variant of PPP2R5D (Q14738)
G76G (p.Gly76Gly) in PPP2R5D (Q14738) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
G76G (p.Gly76Gly) variant details
- p.Gly76Gly
- gnomAD 6-43006585-G-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.402
- AlphaMissense 0.09
- MetaLR 0.29
- MetaSVM -0.85
- CADD 10.80
- PolyPhen-2 0.98
- SIFT 0.21
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available