V28I (p.Val28Ile) variant of PPM1D (Protein phosphatase 1D)
V28I (p.Val28Ile) in PPM1D (Protein phosphatase 1D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
V28I (p.Val28Ile) variant details
- p.Val28Ile
- ExAC rs756726983
- gnomAD rs756726983
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.07
- CADD 20.70
- PolyPhen-2 0.01
- SIFT 0.65
- Most common in the Latino/Admixed American population (allele frequency 2.7e-05)
- Structural context available