T25S (p.Thr25Ser) variant of PPM1D (Protein phosphatase 1D)
T25S (p.Thr25Ser) in PPM1D (Protein phosphatase 1D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
T25S (p.Thr25Ser) variant details
- p.Thr25Ser
- gnomAD 17-60600487-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.07
- MetaLR 0.06
- MetaSVM -1.17
- CADD 25.90
- PolyPhen-2 0.87
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available