T25P (p.Thr25Pro) variant of PPM1D (Protein phosphatase 1D)
T25P (p.Thr25Pro) in PPM1D (Protein phosphatase 1D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
T25P (p.Thr25Pro) variant details
- p.Thr25Pro
- gnomAD 17-60600487-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.308
- REVEL 0.10
- MetaLR 0.06
- MetaSVM -1.16
- CADD 27.80
- PolyPhen-2 0.94
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available