T25N (p.Thr25Asn) variant of PPM1D (Protein phosphatase 1D)
T25N (p.Thr25Asn) in PPM1D (Protein phosphatase 1D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
T25N (p.Thr25Asn) variant details
- p.Thr25Asn
- gnomAD 17-60600488-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.36
- REVEL 0.12
- MetaLR 0.07
- MetaSVM -1.16
- CADD 25.30
- PolyPhen-2 0.94
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available