T25A (p.Thr25Ala) variant of PPM1D (Protein phosphatase 1D)
T25A (p.Thr25Ala) in PPM1D (Protein phosphatase 1D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
T25A (p.Thr25Ala) variant details
- p.Thr25Ala
- gnomAD 17-60600487-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.07
- MetaLR 0.04
- MetaSVM -1.16
- CADD 26.00
- PolyPhen-2 0.60
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available