P33P (p.Pro33Pro) variant of PPM1D (Protein phosphatase 1D)
P33P (p.Pro33Pro) in PPM1D (Protein phosphatase 1D) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
P33P (p.Pro33Pro) variant details
- p.Pro33Pro
- rs1312084710
- gnomAD 17-60600513-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.472
- AlphaMissense 0.91
- MetaLR 0.83
- MetaSVM 0.79
- CADD 10.80
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the South Asian population (allele frequency 3.7e-05)
- Structural context available
- Literature evidence available