P31P (p.Pro31Pro) variant of PPM1D (Protein phosphatase 1D)
P31P (p.Pro31Pro) in PPM1D (Protein phosphatase 1D) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
P31P (p.Pro31Pro) variant details
- p.Pro31Pro
- rs779202711
- gnomAD 17-60600507-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.368
- AlphaMissense 0.18
- MetaLR 0.35
- MetaSVM -0.29
- CADD 10.70
- PolyPhen-2 0.54
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available