M21V (p.Met21Val) variant of PPM1D (Protein phosphatase 1D)
M21V (p.Met21Val) in PPM1D (Protein phosphatase 1D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
M21V (p.Met21Val) variant details
- p.Met21Val
- gnomAD 17-60600475-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.421
- REVEL 0.33
- MetaLR 0.07
- MetaSVM -1.13
- CADD 27.10
- PolyPhen-2 0.97
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available