M21T (p.Met21Thr) variant of PPM1D (Protein phosphatase 1D)
M21T (p.Met21Thr) in PPM1D (Protein phosphatase 1D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
M21T (p.Met21Thr) variant details
- p.Met21Thr
- gnomAD 17-60600476-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.45
- REVEL 0.38
- MetaLR 0.07
- MetaSVM -1.13
- CADD 28.70
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available