G17W (p.Gly17Trp) variant of PPM1D (Protein phosphatase 1D)
G17W (p.Gly17Trp) in PPM1D (Protein phosphatase 1D) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
G17W (p.Gly17Trp) variant details
- p.Gly17Trp
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.61
- REVEL 0.46
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available