A35S (p.Ala35Ser) variant of PPM1D (Protein phosphatase 1D)
A35S (p.Ala35Ser) in PPM1D (Protein phosphatase 1D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
A35S (p.Ala35Ser) variant details
- p.Ala35Ser
- gnomAD 17-60600517-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -1.04
- CADD 14.10
- PolyPhen-2 0.04
- SIFT 0.47
- Population evidence available
- Structural context available
- Literature evidence available