A35D (p.Ala35Asp) variant of PPM1D (Protein phosphatase 1D)
A35D (p.Ala35Asp) in PPM1D (Protein phosphatase 1D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
A35D (p.Ala35Asp) variant details
- p.Ala35Asp
- gnomAD 17-60600518-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.03
- MetaLR 0.06
- MetaSVM -1.05
- CADD 15.90
- PolyPhen-2 0.00
- SIFT 0.39
- Population evidence available
- Structural context available
- Literature evidence available