S165T (p.Ser165Thr) variant of PPARGC1A (Q9UBK2)
S165T (p.Ser165Thr) in PPARGC1A (Q9UBK2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S165T (p.Ser165Thr) variant details
- p.Ser165Thr
- TOPMed rs542146598
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.12
- CADD 18.40
- PolyPhen-2 0.03
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available