S74F (p.Ser74Phe) variant of PPARG (P37231)
S74F (p.Ser74Phe) in PPARG (P37231) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and published literature.
S74F (p.Ser74Phe) variant details
- p.Ser74Phe
- gnomAD 3-12381346-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.784
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Literature evidence available