S46F (p.Ser46Phe) variant of PPARG (P37231)
S46F (p.Ser46Phe) in PPARG (P37231) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and published literature.
S46F (p.Ser46Phe) variant details
- p.Ser46Phe
- gnomAD 3-12379833-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.77
- CADD 25.20
- PolyPhen-2 0.60
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Literature evidence available