S22F (p.Ser22Phe) variant of PPARG (P37231)
S22F (p.Ser22Phe) in PPARG (P37231) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data, published literature, and structural context.
S22F (p.Ser22Phe) variant details
- p.Ser22Phe
- rs372494308
- gnomAD 3-12379773-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.77
- CADD 24.20
- PolyPhen-2 0.85
- SIFT 0.06
- Most common in the Middle Eastern population (allele frequency 0.00035)
- Structural context available
- Literature evidence available