L21V (p.Leu21Val) variant of PPARG (P37231)
L21V (p.Leu21Val) in PPARG (P37231) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
L21V (p.Leu21Val) variant details
- p.Leu21Val
- rs751292113
- gnomAD 3-12379769-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.724
- CADD 22.30
- PolyPhen-2 0.07
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- Literature evidence available