L21R (p.Leu21Arg) variant of PPARG (P37231)
L21R (p.Leu21Arg) in PPARG (P37231) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
L21R (p.Leu21Arg) variant details
- p.Leu21Arg
- rs1235373823
- gnomAD 3-12379770-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.641
- CADD 26.00
- PolyPhen-2 0.91
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available