I49T (p.Ile49Thr) variant of POT1 (Q9NUX5)

I49T (p.Ile49Thr) in POT1 (Q9NUX5) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Hereditary cancer-predisposing syndrome; not provided; Tumor predisposition synd. The record also includes published literature and structural context.

I49T (p.Ile49Thr) variant details