T25I (p.Thr25Ile) variant of POLR1D (P0DPB6)
T25I (p.Thr25Ile) in POLR1D (P0DPB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
T25I (p.Thr25Ile) variant details
- p.Thr25Ile
- TOPMed rs777412814
- gnomAD rs777412814
- Missense
- Variant Prioritization Score for Impact Estimate 0.514
- REVEL 0.37
- CADD 21.50
- PolyPhen-2 0.01
- SIFT 0.17
- Population evidence available
- Structural context available