S41T (p.Ser41Thr) variant of POLH (DNA polymerase eta)
S41T (p.Ser41Thr) in POLH (DNA polymerase eta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
S41T (p.Ser41Thr) variant details
- p.Ser41Thr
- gnomAD 6-43582440-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.15
- ESM-1b 0.00
- AlphaMissense 0.06
- MetaLR 0.06
- MetaSVM -1.10
- CADD 12.80
- Population evidence available
- Structural context available
- Literature evidence available