G58G (p.Gly58Gly) variant of POLH (DNA polymerase eta)
G58G (p.Gly58Gly) in POLH (DNA polymerase eta) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
G58G (p.Gly58Gly) variant details
- p.Gly58Gly
- rs766522721
- gnomAD 6-43583043-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.154
- CADD 10.30
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available