G4G (p.Gly4Gly) variant of POLH (DNA polymerase eta)
G4G (p.Gly4Gly) in POLH (DNA polymerase eta) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
G4G (p.Gly4Gly) variant details
- p.Gly4Gly
- gnomAD 6-43582331-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.254
- CADD 12.90
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available