D66D (p.Asp66Asp) variant of POLH (DNA polymerase eta)
D66D (p.Asp66Asp) in POLH (DNA polymerase eta) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
D66D (p.Asp66Asp) variant details
- p.Asp66Asp
- gnomAD 6-43583067-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.425
- CADD 11.40
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available