A35A (p.Ala35Ala) variant of POLH (DNA polymerase eta)
A35A (p.Ala35Ala) in POLH (DNA polymerase eta) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
A35A (p.Ala35Ala) variant details
- p.Ala35Ala
- gnomAD 6-43582424-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.164
- CADD 11.70
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available