A10T (p.Ala10Thr) variant of POLH (DNA polymerase eta)
A10T (p.Ala10Thr) in POLH (DNA polymerase eta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
A10T (p.Ala10Thr) variant details
- p.Ala10Thr
- gnomAD 6-43582347-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.533
- REVEL 0.46
- ESM-1b 1.00
- AlphaMissense 0.22
- MetaLR 0.25
- MetaSVM -0.41
- CADD 23.50
- Population evidence available
- Structural context available
- Literature evidence available