P35S (p.Pro35Ser) variant of POLG (DNA polymerase subunit gamma-1)
P35S (p.Pro35Ser) in POLG (DNA polymerase subunit gamma-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
P35S (p.Pro35Ser) variant details
- p.Pro35Ser
- cosmic curated COSV51522
- Missense
- Variant Prioritization Score for Impact Estimate 0.212
- REVEL 0.17
- CADD 16.20
- PolyPhen-2 0.00
- SIFT 0.36
- Population evidence available
- Structural context available