D22Y (p.Asp22Tyr) variant of POLE (Q07864)

D22Y (p.Asp22Tyr) in POLE (Q07864) is a missense change. Clinical records from ClinVar and UniProt describe it as uncertain significance in the context of Hereditary cancer-predisposing syndrome. The record also includes structural context.

D22Y (p.Asp22Tyr) variant details