D22N (p.Asp22Asn) variant of POLE (Q07864)

D22N (p.Asp22Asn) in POLE (Q07864) is a missense change. Clinical records from ClinVar and UniProt describe it as uncertain significance in the context of Hereditary cancer-predisposing syndrome; Polymerase proofreading-related adenoma. The record also includes structural context.

D22N (p.Asp22Asn) variant details