T85P (p.Thr85Pro) variant of POGZ (Q7Z3K3)
T85P (p.Thr85Pro) in POGZ (Q7Z3K3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
T85P (p.Thr85Pro) variant details
- p.Thr85Pro
- ExAC rs752956743
- TOPMed rs752956743
- gnomAD rs752956743
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.24
- ESM-1b 0.00
- AlphaMissense 0.29
- CADD 23.90
- PolyPhen-2 0.36
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available